.. _alanine-aminotransferase:

`Back to overview <https://genrisk.readthedocs.io/en/latest/real_cases.html#other-phenotypes>`_

Alanine Aminotransferase Association Analysis
==============================================

Download :download:`full summary statistics <../../association_results/linear_assoc_alanine_aminotransferase_cov_filtered.csv>`

.. csv-table:: Alanine Aminotransferase associations
   :delim: ;
   :header-rows: 1

   genes;p_value;beta_coef;std_err;fdr_bh_adj_pval
   GPT;1,77E-180;-0.05442318587986155;0.0018171563850382265;3,28E-178
   THRA;1,69E+08;0.03540847881846632;0.006276194991673546;0.00015650150581636955
   HIST1H4J;1,50E+11;0.055788337474851214;0.012886063949944453;0.06889346728252056
   ANKH;1,65E+10;-0.01390070258016601;0.0032265426059549522;0.06889346728252056
   YPEL5;2,00E+11;0.1183617099791475;0.027751095876026078;0.06889346728252056
   RSPO3;2,23E+11;0.032355869443085265;0.007629484131767151;0.06889346728252056
   RWDD3;3,24E+10;0.026515466522007175;0.006379498946333348;0.07536387840813479
   DCAF8L2;3,25E+10;0.048990312805228024;0.01178957389077094;0.07536387840813479
   ABCC2;3,92E+11;0.004697131451681245;0.0011422026749874764;0.07863285572857773
   DHH;4,39E+10;0.02124125904129047;0.00519860507113045;0.07863285572857773
   LBX1;5,07E+09;0.014345844667390643;0.003540192897372571;0.07863285572857773
   VWC2L;5,09E+10;0.01727298340598915;0.004263038001378872;0.07863285572857773
   ADGRE3;7,54E+10;0.007730696067705759;0.0019528221504048148;0.10760352119272137
   TMC4;9,12E+09;0.010745909286454865;0.002746240625576324;0.12090017668455923
   CEP112;0.00011581023805606117;0.005650921028340261;0.0014658927687591255;0.14155744432790862
   TAC3;0.00012205858532262006;0.04170151888709683;0.010853952407633824;0.14155744432790862
   SLC30A10;0.00021793599775212467;0.012860489371687591;0.0034782926767219806;0.2378835514287309
   PHF6;0.00024680399843052627;0.08339523095053483;0.02275049478243947;0.24466145503996747
   ACVR2B;0.00027236716089838503;0.014532906268562455;0.0039921781103055215;0.24466145503996747
   SHBG;0.00030650619671494914;0.011185530317971778;0.0030986348118453534;0.24466145503996747
   CAAP1;0.0003077495125392942;0.008764280136615354;0.0024286025602254452;0.24466145503996747
   C1orf68;0.0003185224178364275;0.022255792128653158;0.006182444236378091;0.24466145503996747
   ZCCHC6;0.0003215795611924936;0.006510488527011383;0.0018098001199900796;0.24466145503996747
   CBLL1;0.00032709343404200387;0.023621809903678747;0.00657453292581491;0.24466145503996747
   SMC1B;0.00032962580168135303;0.011272358139173145;0.0031391313040038792;0.24466145503996747
   KRT32;0.00036281209577101504;0.00886048165038957;0.0024848247019147772;0.2589362018894983
   CHST9;0.0004054434841258638;0.011833677507659282;0.0033460631923015677;0.2786447885718344
   EIF4ENIF1;0.00044775286725782246;-0.00581573312135775;0.0016567669292469006;0.2887962376069731
   C11orf71;0.0004617205481426396;0.03736564358159515;0.010669453925446411;0.2887962376069731
   MVB12B;0.0004669048894270959;0.023519041069384954;0.006721381874559413;0.2887962376069731


The QQ-plot:
------------
.. image:: ../../association_results/linear_assoc_alanine_aminotransferase_cov_filtered_qqplot.png
    :width: 400
    :align: center

The Manhattan plot:
--------------------
.. image:: ../../association_results/linear_assoc_alanine_aminotransferase_cov_filtered_manhattan.png
    :width: 400
    :align: center